自引率: 25.9%
被引量: 10537
通过率: 暂无数据
审稿周期: 4.33
版面费用: 暂无数据
国人发稿量: 39
投稿须知/期刊简介:
The journal is a forum for the original scientific results of basic applied and clinical research involving any aspect of the pineal gland or its hormonal products in all vertebrate species. Essential criteria for publication are soundness novelty and timeliness as well as clarity of presentation. Experimental data that are contrary to currently accepted thinking or divergent from actual dogma will be considered provided the findings are based on solid new experimental observations. All submitted papers must be complete in themselves. Case reports will be considered if the findings contribute significantly to an understanding of some aspect of the pineal gland. It is the expressed aim of the journal to serve pineal researchers in all disciplines.
期刊描述简介:
The journal is a forum for the original scientific results of basic applied and clinical research involving any aspect of the pineal gland or its hormonal products in all vertebrate species. Essential criteria for publication are soundness novelty and timeliness as well as clarity of presentation. Experimental data that are contrary to currently accepted thinking or divergent from actual dogma will be considered provided the findings are based on solid new experimental observations. All submitted papers must be complete in themselves. Case reports will be considered if the findings contribute significantly to an understanding of some aspect of the pineal gland. It is the expressed aim of the journal to serve pineal researchers in all disciplines.
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Melatonin Regulates Rheumatoid Synovial Fibroblasts-Related Inflammation: Implications for Pathological Skeletal Muscle Treatment.
被引量：- 发表：2024
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Melatonin Attenuates Diabetic Retinopathy by Regulating EndMT of Retinal Vascular Endothelial Cells via Inhibiting the HDAC7/FOXO1/ZEB1 Axis.
被引量：- 发表：2024
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Melatonin Prevents Thioacetamide-Induced Gut Leakiness and Liver Fibrosis Through the Gut-Liver Axis via Modulating Sirt1-Related Deacetylation of Gut Junctional Complex and Hepatic Proteins.
被引量：- 发表：2024
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Melatonin Regulates Neuronal Synaptic Plasticity in the Supramammillary Nucleus and Attenuates Methamphetamine-Induced Conditioned Place Preference and Sensitization in Mice.
Methamphetamine (METH) is an addictive drug that threatens human health. The supramammillary nucleus (SuM) and its neural circuits play key roles in the regulation of spatial memory retrieval, and hippocampal contextual or social memory. Melatonin (MLT), a pineal hormone, can regulate hypothalamic-neurohypophysial activity. Our previous study showed that MLT attenuates METH-induced locomotor sensitization. However, whether MLT regulates SuM function and participates in METH-induced contextual memory retrieval remains unclear. Using a mouse model of METH-conditioned place preference (CPP) and sensitization, we found that METH activated c-Fos expression and elevated calcium (Ca²⁺) levels in SuM neurons. Chemogenetic inhibition of SuM attenuates CPP and sensitization. Pretreatment with MLT decreased c-Fos expression and Ca2+ levels in the SuM and reversed METH-induced addictive behavior, effects that were blocked with the selective MT2 receptors antagonist 4P-PDOT and the MT1 receptors antagonist S26131. Furthermore, MLT reduced SuM synaptic plasticity, glutamate (Glu) release, and neuronal oscillations caused by METH, which were blocked by 4P-PDOT. In conclusion, our data revealed that MLT regulates neuronal synaptic plasticity in the SuM, likely through the MLT receptors (MTs), and plays a role in modulating METH-addictive behavior.
被引量：- 发表：2024
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Criticism on the Incorrect Use of Oxygen-Ozone Therapy in Medicine.
被引量：- 发表：2024
