自引率: 8%
被引量: 9714
通过率: 暂无数据
审稿周期: 1.8
版面费用: 暂无数据
国人发稿量: 54
投稿须知/期刊简介:
Brain Research Bulletin is dedicated to the rapid publication of significant research articles and reviews in all areas of the neurosciences. In addition to reports of original research, the journal also publishes general and speculative reviews, topical debates, methodological developments, theoretical articles and occasional special issues. The editors are committed to maintaining a high quality of all published reports and to a rapid and fair review process. Manuscripts will be subject to a process of anonymous review (the names of authors and their affiliations will be disclosed to the referees only when the review process is complete). Accelerated publication is the goal for all manuscripts. Articles will be published in English. To link to the editorial office homepage: http://www.brb.cf.ac.uk
期刊描述简介:
Brain Research Bulletin is dedicated to the rapid publication of significant research articles and reviews in all areas of the neurosciences. In addition to reports of original research, the journal also publishes general and speculative reviews, topical debates, methodological developments, theoretical articles and occasional special issues. The editors are committed to maintaining a high quality of all published reports and to a rapid and fair review process. Manuscripts will be subject to a process of anonymous review (the names of authors and their affiliations will be disclosed to the referees only when the review process is complete). Accelerated publication is the goal for all manuscripts. Articles will be published in English. To link to the editorial office homepage: http://www.brb.cf.ac.uk
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Receivers' responses are integrated into costly third-party punishment in a way that interacts with the unfairness of allocations.
被引量：- 发表：1970
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Investigating the mechanisms of inflammation and immune alterations in Parkinson's disease using spatial transcriptomics techniques.
被引量：- 发表：1970
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Bleomycin triggers chronic mechanical nociception by activating TRPV1 and glial reaction-mediated neuroinflammation via TSLP/TSLPR/pSTAT5 signals.
被引量：- 发表：1970
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Quercetin alleviates microglial-induced inflammation after traumatic brain injury via the PGC-1α/Nrf2 pathway dependent on HDAC3 inhibition.
被引量：- 发表：1970
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Neuregulin-1 immunoreactivity in peripheral plasma is associated with rs6982890 polymorphism-mediated psychotic symptoms in schizophrenia.
Neuregulin 1 (NRG1) is a risk gene for schizophrenia and involved in neurodevelopment and synaptic plasticity. Polymorphisms in NRG1 may affect psychotic symptoms in schizophrenia. This study investigated the effects of the single nucleotide polymorphism (SNP) rs6982890 on peripheral plasma NRG1 immunoreactivity, clinical symptoms and cognitive functions in schizophrenia patients. We recruited subjects from the Han population of northern China from 2010 to 2022. We first genotyped and analyzed 6 NRG1 SNPS in 1304 patients with schizophrenia and 871 healthy controls. Then, 91 patients with schizophrenia and 40 healthy controls were selected to detect the peripheral plasma NRG1 immunoreactivity by ELISA. Among them, 84 patients were divided into rs6982890 genotypes to analyze the correlation between NRG1 immunoreactivity and clinical symptoms. Rs6982890 allelic frequencies were statistically significant between patients and controls. Baseline peripheral plasma NRG1 immunoreactivity in patients were significantly lower than controls. NRG1 immunoreactivity in patients were significantly increased after 8 weeks of antipsychotic treatment and significantly correlated with clinical symptoms and cognitive function. Genotyping of patients with SNP rs6982890 indicated NRG1 immunoreactivity in CC genotype increased significantly after treatment, while CT genotype had no significant change. Baseline NRG1 immunoreactivity with the CT genotype were significantly higher than CC genotype. NRG1 SNP rs6982890 is significantly associated with schizophrenia in the Han population of northern China, and it may affect the effect of antipsychotic drug treatment by regulating the peripheral plasma NRG1 immunoreactivity.
被引量：- 发表：1970
