自引率: 5.2%
被引量: 10629
通过率: 暂无数据
审稿周期: 1
版面费用: 暂无数据
国人发稿量: 23
投稿须知/期刊简介:
The American Journal of Hematology provides broad coverage of both human and animal hematologic topics. The journal publishes original contributions from investigators and clinicians in hematology and related areas such as immunology blood banking and cell biology. The journal includes original laboratory and clinical studies concise reviews brief reports images in hematology clinical studies in hemostasis and thrombosis letters and correspondence and occasional in-depth reviews of selected topics.
期刊描述简介:
The American Journal of Hematology provides broad coverage of both human and animal hematologic topics. The journal publishes original contributions from investigators and clinicians in hematology and related areas such as immunology blood banking and cell biology. The journal includes original laboratory and clinical studies concise reviews brief reports images in hematology clinical studies in hemostasis and thrombosis letters and correspondence and occasional in-depth reviews of selected topics.
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Measurable residual disease monitoring in AML: Prospects for therapeutic decision-making and new drug development.
被引量：- 发表：1970
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Assessing acute toxicity profiles of HLA-identical hematopoietic stem cell transplantation in pediatric patients with sickle cell anemia: A comprehensive analysis on behalf of the SFGM-TC.
被引量：- 发表：1970
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Comparison of prognostic scores according to WHO classification in 170 patients with advanced mastocytosis and C-finding treated with midostaurin.
被引量：- 发表：1970
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Clearance of pathogenic erythrocytes is maintained despite spleen dysfunction in children with sickle cell disease.
被引量：- 发表：1970
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Posttraumatic stress disorder increases thrombosis risk: Evidence from a biobank data set.
Depression and anxiety are linked to deep venous thrombosis (DVT) and posttraumatic disorder (PTSD) increases risk of venous thromboembolism in women. However, the mechanisms underlying this relationship remain unknown. We hypothesized that PTSD would associate with increased DVT risk, that neuroimmune mechanisms would mediate the PTSD-DVT link, and that these associations would be stronger in women. This cohort study included N = 106 427 participants from a large biobank. PTSD and DVT were defined using ICD-10 codes. A subset (N = 1520) underwent imaging, from which we assessed stress-associated neural activity (SNA). High-sensitivity C-reactive protein (hs-CRP) levels and heart rate variability (HRV) were used as indicators of systemic inflammation and autonomic activity, respectively. Linear, logistic, and Cox regressions and mediation analyses were used to test our hypotheses. Of 106 427 participants, 4192 (3.9%) developed DVT. PTSD associated with increased DVT risk (HR [95% CI]: 1.66 [1.34, 2.07], p < .001), and this finding remained significant after adjustment for age, sex, and traditional DVT risk factors. When analyzed separately by sex, PTSD was significantly associated with DVT risk in women but not men. Further, heightened SNA and lower HRV mediated the effect of PTSD on DVT risk. Results suggest that individuals with PTSD are at increased risk for DVT, and that risk is higher in women. This relationship was partially driven by alterations in stress-associated neural activity and autonomic function, suggesting potential targets for preventive therapies. Future studies are needed to investigate whether intervening on PTSD-DVT mechanisms has downstream beneficial effects on DVT, especially among women.
被引量：- 发表：1970
