自引率: 7.7%
被引量: 2224
通过率: 暂无数据
审稿周期: 1.67
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国人发稿量: 24
投稿须知/期刊简介:
An international journal for the publication of papers concerning research into human population biology, reporting investigations on the nature, development and causes of human variation, embracing the disciplines of human genetics, auxology, environmental physiology, ecology, epidemiology and aging. Annals of Human Biology is the official journal of the Society for the Study of Human Biology .
期刊描述简介:
An international journal for the publication of papers concerning research into human population biology, reporting investigations on the nature, development and causes of human variation, embracing the disciplines of human genetics, auxology, environmental physiology, ecology, epidemiology and aging. Annals of Human Biology is the official journal of the Society for the Study of Human Biology .
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Latitudinal patterns in human stature and sexual stature dimorphism.
There exists substantial variation in human stature and sexual stature dimorphism that has been attributed to both genetic and environmental variables. A few studies have previously investigated possible relationships between latitude and stature, building on the idea that variation in climate can influence body size (Bergmann's rule). This change in body size can in turn have influenced sexual stature dimorphism (in accordance with Rensch's rule). The present study investigated whether latitude is associated with variation in human mean stature and sexual stature DIMORPHISM. Phylogenetic and non-phylogenetic analyses were conducted on a cross-cultural sample of 124 human populations. The results indicate that both male and female mean stature increase with increasing distance from the equator. While sexual stature dimorphism also was positively related to latitude in the non-phylogenetic test, this relationship disappeared when using a phylogenetic comparative method. Evidence was also found for curved relationships between latitude and both male and female stature, as well as stature dimorphism, all indicating a maximum at around 40 degrees from the equator. The results of the present study indicate that both male and female stature are weakly associated with latitude. It is possible that these relationships are evolved responses to variation in climate. No unequivocal conclusion could be drawn regarding a possible relationship between latitude and sexual stature dimorphism.
被引量：8 发表：2009
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HUMTH01, HUMVWA31A, HUMCSF1PO and HUMTPOX polymorphisms in Amerindian populations living in the Beni department of Bolivia.
This report presents allele frequency and absolute genotype data of the short tandem repeat (STR) loci HUMTH01, HUMVWA31A, HUMCSF1PO and HUMTPOX for three autochthonous Amerindian populations living in the Beni Department of Bolivia. These related groups are the Quechua, Aymara and Beni populations all living in specific although sometimes overlapping areas that extend from the Andean habitat to the lowland Llanos de Moxos savannah passing through the Piedmont hills. The usefulness of these loci for paternity and identification testing was also examined. The present work completes previous genetic studies performed by the authors in these populations including mtDNA haplogroups (Bert et al., Hum Biol, 73:1-16, 2001) and HVRI data (Bert et al., Ann Hum Biol 31:9-28, 2004; Corella et al., Ann Hum Biol 34:34-35, 2007).
被引量：- 发表：2008
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Mitochondrial DNA diversity of the Amerindian populations living in the Andean Piedmont of Bolivia: Chimane, Moseten, Aymara and Quechua.
Chimane, Moseten Aymara and Quechua are Amerindian populations living in the Bolivian Piedmont, a characteristic ecoregion between the eastern slope of the Andean mountains and the Amazonian Llanos de Moxos. In both neighbouring areas, dense and complex societies have developed over the centuries. The Piedmont area is especially interesting from a human peopling perspective since there is no clear evidence regarding the genetic influence and peculiarities of these populations. This land has been used extensively as a territory of economic and cultural exchange between the Andes and Amazonia, however Chimane and Moseten populations have been sufficiently isolated from their neighbour groups to be recognized as distinct populations. Genetic information suggests that evolutionary processes, such as genetic drift, natural selection and genetic admixture have formed the history of the Piedmont populations. The objective of this study is to characterize the genetic diversity of the Piedmont populations, analysing the sequence variability of the HVR-I control region in the mitochondrial DNA (mtDNA). Haplogroup mtDNA data available from the whole of Central and South America were utilized to determine the relationship of the Piedmont populations with other Amerindian populations. Hair pulls were obtained in situ, and DNA from non-related individuals was extracted using a standard Chelex 100 method. A 401 bp DNA fragment of HVR-I region was amplified using standard procedures. Two independent 401 and 328 bp DNA fragments were sequenced separately for each sample. The sequence analyses included mismatch distribution and mean pairwise differences, median network analyses, AMOVA and principal component analyses. The genetic diversity of DNA sequences was measured and compared with other South Amerindian populations. The genetic diversity of 401 nucleotide mtDNA sequences, in the hypervariable Control Region, from positions 16 000-16 400, was characterized in a sample of 46 Amerindians living in the Piedmont area in the Beni Department of Bolivia. The results obtained indicate that the genetic diversity in the area is higher than that observed in other American groups living in much larger areas and despite the reduced size of the studied area the human groups analysed show high levels of inter-group variability. In addition, results show that Amerindian populations living in the Piedmont are genetically more related to those in the Andean than in the Amazonian populations.
被引量：12 发表：2007
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Mitochondrial DNA diversity in the Llanos de Moxos: Moxo, Movima and Yuracare Amerindian populations from Bolivia lowlands.
Movima, Yuracare, Ignaciano and Trinitario are Amerindian populations living in the Bolivian lowlands of the Amazonian basin. The cultural and genetic affinity of the peoples living in this area is poorly known, despite many archaeological studies demonstrating its importance in pre-Columbian times. Densely populated Amerindian groups occupied the region, both in the Llanos and along the river streams of the Amazonian basin, practising intense agricultural activities and exchange of goods. The historical and linguistic records indicate that the land was occupied through successive migrations that gave rise to complex socio-economic communities. Genetic information suggests that the colonization of the American continent was fairly simple from a emigrational point of view, but other evolutionary processes, such as genetic drift or natural selection, could have also shaped the genetic background of present day populations in the Beni region. The objective of this study is to characterize the genetic diversity of these populations by analysing the sequence variability of the HVR-I control region in the mitochondrial DNA (mtDNA). The Amerindian origin of these populations suggests that close genetic similarities should be evident between the Beni samples studied here and other Amerindian groups. However, complex processes of population interactions and/or isolation in the Beni region might result in non-expected genetic affinities. DNA was extracted from pulled-out hairs obtained in situ from non-closely related individuals living in the Beni Department in Bolivia. DNA was extracted using a standard Chelex 100 method and a 401 bp DNA fragment of the HVR-I region was amplified using specific primers (L-15978 and H-16412). DNA amplicons were purified by centrifugation using Microspin S-300 HR columns and both SNA strands were sequenced after asymmetric PCR using direct Dye-Terminator 2 sequencing kit (Perkin-Elmer). Two independent 401 and 328 bp DNA fragments were sequenced separately for each sample. The sequence analyses includes mismatch distributions and mean pairwise differences, median network analysis, and neighbour joining, maximum likelihood phylogenetic comparisons. Genetic diversity of DNA sequences was also measured in various ways for the sample studied and UPGMA trees were drawn, including a large number of South Amerindian sequences. The genetic diversity of 401 nucleotide long mtDNA sequences in the hypervariable control region, from positions 16,000-16,400, was characterized in a sample of 54 Amerindians living in the Llanos de Moxos. A total of 34 distinct lineages were observed, defined by 41 variable nucleotide positions, and 70.6% of all lineages were single sequences. All four major Amerindian haplogroups were detected (A 18.5%, n=10; B 24.1%, n=13, C 50.0% n=27; and D 5.6%, n=3). The median network analysis observed suggests that processes of population expansion took place in the Beni region. However, no clear haplotype differentiation by population could be detected. High levels of molecular variability and a bimodal pair-wise mismatch distribution were seen within the sample. The analyses of molecular variance (AMOVA) showed that most of the variance observed was due to intrapopulation variability, and that the highest among-groups variance was obtained when a linguistic classification criteria was used. The phylogenetic comparison revealed unique lineages in the Beni areas, not reported for other Amerindian populations. The genetic diversity observed in the Beni area is higher than that observed in other American populations living in much larger areas and with a long, known evolutionary history, despite the reduced area of Moxos. This could result from processes of reproductive isolation between groups, followed by population expansions and migration, where genetic drift might have be a major evolutionary force in population differentiation.
被引量：- 发表：2004
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Daily rat tibial growth in vivo following hypothalamic sex reversal with neonatal and pubertal treatments with gonadal steroids.
:A striking sex-related difference in postpubertal growth and growth hormone (GH) secretory pattern in the rat has been described. Although this sexual dimorphism seems to be determined by the neonatal effects of gonadal steroids on the hypothalamus, peripubertal exposure to steroids also plays an important role. In order to study the real influence of the hypothalamic sex and/or peripubertal gonadal steroids, the growth pattern of female and male rats in response to neonatal and peripubertal sexual steroid treatments was studied using microknemometry, a technique that allows non-invasive daily measurements of rat tibial growth rate. Neonatal steroid environment in males was modified by castration on day 1, whereas in females it was changed by a single neonatal testosterone administration on day 5 followed by castration at 13 days of age. From the onset of puberty to adulthood, both female and male animals received testosterone or estrogens, respectively. Neonatal treatment alone, i.e. androgenization of female and castration of male rats, were only able to induce a partial reversal of the original sex-dependent growth pattern. Additional peripubertal treatments achieved a complete change in the sex-linked growth pattern. Consistent with the effects observed on growth, the pituitary GH concentration was significantly increased in females, and diminished in males, when they were treated both at the neonatal and peripubertal stages. However, only this latter group, whose growth was more seriously compromised, showed decreased plasma insulin-like growth factor-I (IGF-I) levels. In conclusion, a complete feminization of male tibial growth pattern or masculinization of female pattern can only be achieved by maintaining the new steroid environment from puberty to adulthood.
被引量：1 发表：2001
