
自引率: 8.5%
被引量: 3737
通过率: 暂无数据
审稿周期: 暂无数据
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国人发稿量: 7
投稿须知/期刊简介:
The primary aim of Infection is to be a forum for the presentation and discussion of clinically relevant information on infectious diseases for readers and contributors from all over the world. Articles deal with etiology pathogenesis diagnosis and treatment of infectious diseases in the outpatient as well as in the inpatient setting. Public health -issues of local regional or international importance related to infectious diseases are featured as well as progress and -problems in hospital epidemiology. The main contents of the journal include original articles describing results of research projects brief reports on new observations that enhance the knowledge of clinicians and state-of-the-art reviews on topics which are relevant to physicians diagnosing or treating infectious diseases. Case reports describing new infectious etiologies or clinical manifestations are also welcome. Finally the correspondence section is open to readers who want to respond to articles published in Infection or to succinctly present information to the general readership. Infection adheres to a high standard of quality of all published material. Each article undergoes a peer-review process. At the same time the editors aim to keep the interval between submission and publication as short as possible. For articles describing particularly timely or important new findings accelerated peer-review and fast-track publication is made available.
期刊描述简介:
The primary aim of Infection is to be a forum for the presentation and discussion of clinically relevant information on infectious diseases for readers and contributors from all over the world. Articles deal with etiology pathogenesis diagnosis and treatment of infectious diseases in the outpatient as well as in the inpatient setting. Public health -issues of local regional or international importance related to infectious diseases are featured as well as progress and -problems in hospital epidemiology. The main contents of the journal include original articles describing results of research projects brief reports on new observations that enhance the knowledge of clinicians and state-of-the-art reviews on topics which are relevant to physicians diagnosing or treating infectious diseases. Case reports describing new infectious etiologies or clinical manifestations are also welcome. Finally the correspondence section is open to readers who want to respond to articles published in Infection or to succinctly present information to the general readership. Infection adheres to a high standard of quality of all published material. Each article undergoes a peer-review process. At the same time the editors aim to keep the interval between submission and publication as short as possible. For articles describing particularly timely or important new findings accelerated peer-review and fast-track publication is made available.
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Non-HACEK gram-negative bacilli infective endocarditis: data from a retrospective German cohort study.
被引量:- 发表:1970
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A simple scoring algorithm predicting paravertebral and/or iliopsoas abscess among adults with community-onset bloodstream infections: matters of PVL-producing Staphylococcus aureus.
被引量:- 发表:1970
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HEV-3 subtypes and strains detected in cases of HEV infection in central Italy from 2015 to 2023.
HEV is an emerging pathogen in Europe and was previously shown to be hyperendemic in areas of Abruzzo and Lazio, Central Italy. No systematic analysis of the HEV strains responsible for human infections over several years in Central Italy has previously been reported. Aim of the study was the molecular characterization of HEV from autochthonous hepatitis E cases occurred in Abruzzo and Lazio between 2015 and 2023. Samples from 118 cases collected as part of virological surveillance in Abruzzo and Lazio from 2015 to 2023 were subjected to HEV sequencing and phylogenetic analysis. The main observed subtype was 3f, followed by 3c and 3e. The annual subtype distribution was quite stable over the observation period, but 3f cases tended to concentrate in winter/early spring whereas 3e cases in summer. Phylogenetic clusters of highly related sequences (a) highlighted unrecognized "point source outbreaks", (b) provided molecular support to temporally and/or geographically linked cases and (c) provided evidence for transmission of identical/highly related strains up to months/years following their first detection. The data provide an overview of the HEV strains responsible for human infections over eight years in Central Italy. The observed subtype distribution appears to agree better with the subtype distribution reported in Italy in pigs rather than in geographically matched wild boars, suggesting pig and its derivate food was a more frequent source of infection than wild boar in Abruzzo and Lazio. Molecular characterization is essential to recognize "point source outbreaks" and to monitor HEV circulation.
被引量:- 发表:1970
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Efficacy and safety of colistin plus beta-lactams for bone and joint infection caused by fluoroquinolone-resistant gram-negative bacilli: a prospective multicenter study.
The prognosis of bone and joint infections (BJI) caused by Gram-negative bacilli (GNB) worsens significantly in the face of fluoroquinolone-resistance. In this setting, scarce pre-clinical and clinical reports suggest that intravenous beta-lactams plus colistin may improve outcome. Our aim was to assess the efficacy and safety of this treatment in a well-characterized prospective cohort. Observational, prospective, non-comparative, multicenter (14 hospitals) study of adults with BJI caused by fluoroquinolone-resistant GNB treated with surgery and intravenous beta-lactams plus colistin for ≥ 21 days. The primary endpoint was the cure rate. Of the 44 cases included (median age 72 years [IQR 50-81], 22 [50%] women), 32 (73%) had an orthopedic device-related infection, including 17 (39%) prosthetic joints. Enterobacterales were responsible for 27 (61%) episodes, and Pseudomonas spp for 17 (39%), with an overall rate of MDR/XDR GNB infections of 27/44 (61%). Patients were treated with colistin plus intravenous beta-lactam for 28 days (IQR 22-37), followed by intravenous beta-lactam alone for 19 days (IQR 5-35). The cure rate (intention-to-treat analysis; median follow-up = 24 months, IQR 19-30) was 82% (95% CI 68%-90%) and particularly, 80% (95% CI 55%-93%) among patients managed with implant retention. Adverse events (AEs) leading to antimicrobial withdrawal occurred in 10 (23%) cases, all of which were reversible. Colistin AEs were associated with higher plasma drug concentrations (2.8 mg/L vs. 0.9 mg/L, p = 0.0001). Combination therapy with intravenous beta-lactams plus colistin is an effective regimen for BJI caused by fluoroquinolone-resistant GNB. AEs were reversible and potentially preventable by close therapeutic drug monitoring.
被引量:- 发表:1970
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Maternal Streptococcus agalactiae colonization in Europe: data from the multi-center DEVANI study.
被引量:- 发表:1970