自引率: 1.1%
被引量: 13034
通过率: 暂无数据
审稿周期: 2
版面费用: 暂无数据
国人发稿量: 7
投稿须知/期刊简介:
Trends in Pharmacological Sciences is the leading monthly review journal in pharmacology and toxicology (Impact factor 10.148; SCI Journals Citation Reports 1997). Every issue of Trends in Pharmacology Sciences contains succinct articles on the most exciting recent developments in pharmacology research: topics covered in the journal range from molecular to behavioural pharmacology, and from current techniques to theoretical pharmacology. Trends in Pharmacological Sciences has a prestigious Advisory Editorial Board that attest to the journals established reputation as essential reading for all pharmacologists, from students to professors and directors. Review articles published in Trends in Pharmacological Sciences are lively, well-illustrated and have been thoroughly peer reviewed to ensure a balanced representation of the literature. Careful editing ensures accessibility to the non-specialist without compromising depth or quality for the specialist.
期刊描述简介:
Trends in Pharmacological Sciences is the leading monthly review journal in pharmacology and toxicology (Impact factor 10.148; SCI Journals Citation Reports 1997). Every issue of Trends in Pharmacology Sciences contains succinct articles on the most exciting recent developments in pharmacology research: topics covered in the journal range from molecular to behavioural pharmacology, and from current techniques to theoretical pharmacology. Trends in Pharmacological Sciences has a prestigious Advisory Editorial Board that attest to the journals established reputation as essential reading for all pharmacologists, from students to professors and directors. Review articles published in Trends in Pharmacological Sciences are lively, well-illustrated and have been thoroughly peer reviewed to ensure a balanced representation of the literature. Careful editing ensures accessibility to the non-specialist without compromising depth or quality for the specialist.
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How can quantum computing be applied in clinical trial design and optimization?
被引量：- 发表：1970
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Metabolic regulation in normal and leukemic stem cells.
被引量：- 发表：1970
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Engineering extracellular vesicles for diagnosis and therapy.
被引量：- 发表：1970
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Neurofilament light chain as a biomarker of chemotherapy-induced peripheral neuropathy.
Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of chemotherapy. The frequency of CIPN ranges from one in three to almost all patients depending on type of chemotherapy and dose. It causes symptoms that can range from sensitivity to touch and numbness to neuropathic pain in hands and feet. CIPN is notoriously difficult to grade objectively and has mostly relied on a clinician- or patient-based rating that is subjective and poorly reproducible. Thus, considerable effort has been aimed at identifying objective biomarkers of CIPN. Recent in vitro, animal, and clinical studies suggest that neurofilament light chain (NFL), a structural neuronal protein, may be an objective biomarker of CIPN. NFL released from cells to cell culture media reflects in vitro neurotoxicity, while NFL in serum reflects neuronal damage caused by chemotherapy in rodent models. Finally, NFL in serum may be a diagnostic biomarker of CIPN, but its prognostic ability to predict CIPN requires prospective evaluation. We discuss current limitations and future perspectives on the use of NFL as a preclinical and clinical biomarker of CIPN.
被引量：- 发表：1970
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Spare the pain for your gut Treg cells!
Maintaining gut homeostasis requires a complex interplay between the nervous and immune systems and the microbiome, but the nature of their interactions remains unclear. Chiu and Benoist's teams employed designer receptors exclusively activated by designer drugs (DREADD)-based chemogenetics to target specific neuronal cell types and evaluate their effects on both the gut immune system and the microbiota.
被引量：- 发表：1970
