自引率: 0.2%
被引量: 5009
通过率: 暂无数据
审稿周期: 暂无数据
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投稿须知/期刊简介:
Seminars in Oncology brings you current, authoritative, and practical reviews of developments in the diagnosis and management of patients with cancer. Each issue examines a single topic of clinical importance. You're guided through each cancer's biology, epidemiology, and pathophysiology...its clinical presentation and therapeutic options...and appropriate follow-up measures. This journal makes an excellent addition to every oncology practice.
期刊描述简介:
Seminars in Oncology brings you current, authoritative, and practical reviews of developments in the diagnosis and management of patients with cancer. Each issue examines a single topic of clinical importance. You're guided through each cancer's biology, epidemiology, and pathophysiology...its clinical presentation and therapeutic options...and appropriate follow-up measures. This journal makes an excellent addition to every oncology practice.
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Isolated lung metastases from pancreatic ductal adenocarcinoma (PDAC): Diagnostic and therapeutic challenges of a different disease.
Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis, mostly due to the high rate of distant dissemination. However, growing evidence shows that isolated lung recurrence or metastases (ILM) from PDAC are not only less common, but also correlated with a better prognosis. Lung-only recurrence after surgery occurs later in time and is associated with more favorable prognostic characteristics of the primary tumor. Moreover, recent findings suggest that this specific site of metastases is characterized by an immunologically "hot" microenvironment and a more favorable molecular profile that could possibly justify its clinical behavior. Thus, ILM from PDAC emerge as a distinct entity, that might also benefit from a different therapeutic approach, possibly with the integration of surgery and de-intensified chemotherapy regimens, especially in selected patients. In this review we delve into the current scientific evidence on the clinical and biological characteristics of isolated LM from PDAC, also focusing on concerns with their diagnostic process and the therapeutic options for the management of this subset of patients.
被引量：- 发表：1970
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PARP inhibitors in ovarian cancer.
被引量：- 发表：1970
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CDK4/6 inhibitors in the treatment of metastatic breast cancer: Focus on toxicity and safety.
被引量：- 发表：1970
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Beyond BRCA: Diagnosis and management of homologous recombination repair deficient pancreatic cancer.
被引量：- 发表：1970
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Cancer genetic mutation prevalence in sub-Saharan Africa: A review of existing data.
被引量：- 发表：1970
