自引率: 6.2%
被引量: 7802
通过率: 暂无数据
审稿周期: 6
版面费用: 暂无数据
国人发稿量: 18
投稿须知/期刊简介:
The European Journal of Clinical Pharmacology publishes original papers short communications and letters to the editors on all aspects of clinical pharmacology and drug therapy in humans. Data from animal experiments are accepted only in the context of parallel experiments in man reported in the same paper. The Journal also accepts review articles on special problems related to these areas and encourages debate on controversial issues.
期刊描述简介:
The European Journal of Clinical Pharmacology publishes original papers short communications and letters to the editors on all aspects of clinical pharmacology and drug therapy in humans. Data from animal experiments are accepted only in the context of parallel experiments in man reported in the same paper. The Journal also accepts review articles on special problems related to these areas and encourages debate on controversial issues.
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Comment on "Use of statins and risks of ovarian, uterine, and cervical diseases: a cohort study in the UK Biobank".
被引量：- 发表：1970
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Dose reduction and discontinuation due to the combination of CDK4/6 inhibitors and endocrine drugs: a systematic review and meta-analysis.
被引量：- 发表：1970
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Preventive effects of first-generation antihistamine on emergence agitation or delirium: a systematic review.
The effects of first-generation antihistamines in preventing postoperative emergence agitation or delirium are unclear. Determining the postoperative effects of first-generation antihistamines may provide important insights into the management of patient safety. Therefore, we performed a systematic review of randomized controlled trials (RCTs) evaluating the efficacy and safety of postoperative first-generation antihistamines. Patients who used first-generation antihistamines in the intensive care unit or operating room were included. Primary outcomes were assessed postoperative emergence agitation or delirium with binary and continuous variables. The secondary outcome was any adverse event. Nine studies were included. The frequency of postoperative emergence agitation, measured using binary variables, tended to be lower in patients receiving chlorpheniramine or diphenhydramine than those receiving saline. However, evaluation using the Richmond Agitation-Sedation Scale as a continuous variable revealed that only chlorpheniramine was effective at lowering postoperative emergence agitation. Only one study assessed delirium but found no benefit of first-generation antihistamines. Adverse events for first-generation antihistamines did not differ from that of other drugs. Our results provide limited evidence that some first-generation antihistamines may prevent postoperative emergence agitation and are safe. To further verify this possibility, new RCTs with clear and universal assessment criteria for postoperative emergence agitation or delirium should be conducted.
被引量：- 发表：1970
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Efficacy and safety of ticagrelor monotherapy following a brief DAPT vs. prolonged 12-month DAPT in ACS patients post-PCI: a meta-analysis of RCTs.
被引量：- 发表：1970
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Beta-blockers and breastfeeding: a real-life prospective study.
被引量：- 发表：1970
